投稿分類 防護措施

主委發表種類: 口頭

投稿標題(中): 前瞻性研究預測新型冠狀病毒感染個案到院前心跳停止原因分析

投稿標題(英): Out-of-hospital cardiac arrest among COVID-19 patients: a population-based cohort study

投稿摘要: Introduction: Increased incidence of out-of-hospital cardiac arrest (OHCA) has been reported during the coronavirus disease (COVID-19) pandemic. However, information is lacking on the clinical course and predictors for OHCA in COVID-19 patients. Here, we characterized the clinical course and identified predictors for OHCA among such patients in community isolation centers. Methods: From May 15 to June 20, 2021, this cohort study recruited 2,555 laboratory-confirmed COVID-19 patients admitted to isolation centers in Taiwan. All patients were followed up until death, discharge from the isolation center or hospital, or July 16, 2021. OHCA was defined as cardiac arrest confirmed by the absence of circulation signs and occurring outside the hospital. Multinomial logistic regressions were used to determine factors associated with OHCA and in-hospital cardiac arrest (IHCA). Results: The mean age was 50.8 years, and 1.5% of the patients died during the follow-up period. Of the 37 deceased patients, 7 (18.9%) had OHCA and 30 (81.1%) had IHCA. The mean (SD) time to OHCA was 6.7 (3.1) days from diagnosis of severe acute respiratory syndrome coronavirus 2 infection. After adjusting for demographics and comorbidities, independent predictors for OHCA included aged ≥65 years (adjusted odds ratio [AOR]: 13.24, 95% confidence interval [CI]: 1.85–94.82), fever on admission to the isolation center (AOR: 12.53, 95%CI: 1.68–93.34), and hypoxemia (AOR: 26.54, 95%CI: 3.18–221.73). Conclusions: Time to OHCA occurrence is rapid in COVID-19 patients. Close monitoring of patient vital signs and disease severity during isolation is important, particularly for those with older age, fever, and hypoxemia.

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